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Cardiovascular Disease I
Title
Cardiovascular Disease I
Editor
iConcept Press
Price
USD$109.99
ISBN
978-1-922227-54-6
Clicks
38296

Chapter 1

Cardiovascular Disease I

Renal Artery Diameter: A “New” Parameter Beyond an Old Disease – The Renal Artery Stenosis

by Luca Zanoli, Stefania Rastelli, Paolo Lentini, Carmelita Marcantoni, Davide Capodanno, Enzo Saretto Dante Vicari, Aldo Eugenio Calogero, Antonio Granata, Francesco Rapisarda, Pasquale Fatuzzo and Pietro Castellino

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Abstract

Recently, taking advantage of the cohort of the RAS-CAD Study (NCT 01173666), a large randomized controlled trial aimed to determine whether the stenting of the renal artery is of benefit on the reduction of left ven-tricular mass, our group reported that small renal arteries, for the first time defined by a low reference diameter or minimal luminal diameter, (a) are associated with low GFR and resistant hypertension independently of the degree of stenosis and major confounders, (b) predict the development of contrast-induced nephropathy better than the unspecific baseline reduction of GFR independently of major confounders and (c) could impact the prognosis of patients with ischemic heart disease and non-significant renal artery stenosis (10-70%) independently of major confounders. These results are clinically relevant and suggest that the renal artery diameter could represents a marker of non-traditional cardiovascular risk factors in selected populations. In the present chapter, these results will be presented, and a pathophysiological explanation, including main biophysical background, and the clinical implication of these new findings will be critically discussed.

Author Details

Luca Zanoli
Department of Medical and Pediatric Sciences, University of Catania, Catania, Italy, Italy
Stefania Rastelli
Department of Medical and Pediatric Sciences, University of Catania, Catania, Italy, Italy
Paolo Lentini
Department of Nephrology & Dialysis, San Bassiano Hospital, Bassano del Grappa, Italy, Italy
Carmelita Marcantoni
Department of Nephrology, Cannizzaro Hospital, Catania, Italy, Italy
Davide Capodanno
Cardiovascular Department, Ferrarotto Hospital, Catania, Italy, Italy
Enzo Saretto Dante Vicari
Section of Endocrinology, Andrology and Internal Medicine, Department of Medical and Pediatric Sciences, University of Catania, Catania, Italy, Italy
Aldo Eugenio Calogero
Section of Endocrinology, Andrology and Internal Medicine, Department of Medical and Pediatric Sciences, University of Catania, Catania, Italy, Italy
Antonio Granata
Department of Nephrology, Presidio Ospedaliero Agrigento, Agrigento, Italy, Italy
Francesco Rapisarda
Department of Medical and Pediatric Sciences, University of Catania, Catania, Italy, Italy
Pasquale Fatuzzo
Department of Medical and Pediatric Sciences, University of Catania, Catania, Italy, Italy
Pietro Castellino
Department of Medical and Pediatric Sciences, University of Catania, Catania, Italy, Italy

Citation

Luca Zanoli, Stefania Rastelli, Paolo Lentini, Carmelita Marcantoni, Davide Capodanno, Enzo Saretto Dante Vicari, Aldo Eugenio Calogero, Antonio Granata, Francesco Rapisarda, Pasquale Fatuzzo and Pietro Castellino. Renal Artery Diameter: A “New” Parameter Beyond an Old Disease – The Renal Artery Stenosis. In Cardiovascular Disease I. ISBN:978-1-922227-54-6. iConcept Press. 2014.

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