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Coronary Artery Disease: Research and Practice
Title
Coronary Artery Disease: Research and Practice
Editor
iConcept Press
Price
USD$39.00
ISBN
978-1-922227-98-0
Clicks
7405

Chapter 3

Coronary Artery Disease: Research and Practice

Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials

by Heshu Sulaiman Rahman, Rasedee Abdullah and Hemn Hassan Othman

Viewed: 1432

Abstract

Zerumbone (ZER) is a naturally occurring dietary compound, present in many natural foods consumed today. The compound derived from several plant species of the Zingiberaceae family that has been found to possess multiple biomedical properties, such as antiproliferative, antioxidant, anti-inflammatory, and anticancer activities.However, evidence of efficacy is sparse, pointing to the need for amore systematic reviewfor assessing scientific evidence to support therapeutic claimsmade for ZER and to identify future research needs. This review provides an updated overview of in vitro and in vivo investigations of ZER, its cancer chemopreventive properties, and mechanisms of action.Therapeutic effects of ZER were found to be scientifically plausible and could be explained partially by in vivo and in vitro pharmacological activities. Much of the research outlined in this paper will serve as a foundation to explain ZER anticancer bioactivity, which will open the door for the development of strategies in the treatment of malignancies using ZER.

Author Details

Heshu Sulaiman Rahman
Department of Veterinary Clinical Diagnosis, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Malaysia; Department of Clinic and Internal Medicine, College of Veterinary Medicine, University of Sulaimani, Sulaimani City, Kurdistan Region, Iraq; Department of Medical Laboratory Sciences, College of Health Sciences, Komar University of Science and Technology, Chaq Chaq Qularaisee, Iraq
Rasedee Abdullah
Department of Veterinary Clinical Diagnosis, Faculty of Veterinary Medicine, University Putra Malaysia, Selangor, Malaysia
Hemn Hassan Othman
Institute of Bioscience, Universiti Putra Malaysia, Selangor, Malaysia

Citation

Heshu Sulaiman Rahman, Rasedee Abdullah and Hemn Hassan Othman. Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials. In Coronary Artery Disease: Research and Practice. ISBN:978-1-922227-98-0. iConcept Press. 2016.

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