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Coronary Artery Disease: Research and Practice
Title
Coronary Artery Disease: Research and Practice
Editor
iConcept Press
Price
USD$39.00
ISBN
978-1-922227-98-0
Clicks
7015

Chapter 2

Coronary Artery Disease: Research and Practice

Role of Pericytes and Modified Lipoprotein in Human Atherognesis

by Alexander N Orekhov, Elena R Andreeva, Ekaterina A Ivanova and Yuri V Bobryshev

Viewed: 602

Abstract

Pericytes are pluripotent cells capable of rapid proliferation and participate in immune reactions and can serve as a source of tissue factor inducing thrombus formation. The findings of our research that are highlighted in the chapter, indicate that pericytes, together with other cell types of the arterial wall, actively participate in the development of atherosclerotic lesions and can, therefore, be considered as prospective targets for therapy improvement.

Author Details

Alexander N Orekhov
Institute for Atherosclerosis Research, Skolkovo Innovative Center, Moscow, Russia; Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, Russian Academy of Sciences, Moscow, Russia; Department of Biophysics, Biological Faculty, Moscow State University, Moscow, Russia
Elena R Andreeva
Cell Physiology Laboratory, Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia
Ekaterina A Ivanova
Department of Pediatric Nephrology and Growth and Regeneration, Katholieke Universiteit Leuven and University Hospitals Leuven, Leuven, Belgium
Yuri V Bobryshev
Institute for Atherosclerosis Research, Skolkovo Innovative Center, Moscow, Russia; Faculty of Medicine, School of Medical Sciences, University of New South Wales, Sydney, Australia

Citation

Alexander N Orekhov, Elena R Andreeva, Ekaterina A Ivanova and Yuri V Bobryshev. Role of Pericytes and Modified Lipoprotein in Human Atherognesis. In Coronary Artery Disease: Research and Practice. ISBN:978-1-922227-98-0. iConcept Press. 2016.

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