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Genomics II: Bacteria, Viruses and Metabolic Pathways
Title
Genomics II: Bacteria, Viruses and Metabolic Pathways
Editor
iConcept Press
Price
USD$139.00
ISBN
978-1-480254-145
Clicks
22872

Chapter 10

Genomics II: Bacteria, Viruses and Metabolic Pathways

Structural Insights into the Genome of Viruses

by Jian He, Shuyu Liu, Xiaoqin Zhong, Jingchen Sun, Zheng Liu and Jingqiang Zhang

Viewed: 1960

Abstract

Viruses are one kind of tiny infectious agent that can invade all types of organisms, from animals and plants to bacteria and archaea. Despite the smallest size and the simplest architecture in life system, viruses clearly show many important life characteristics, such as replication and proliferation, genetic variation and evolution, infection and defense, and so on. The virus species are rich, and their structures and functions are also diverse, making viruses an excellent material for sequence and genomic analysis. Thanks to the great advances of structural biology techniques, e.g. cryo-electron microscopy (cryoEM) and X-ray crystallography, studies on the structures and functions of viruses become much easier. Cytoplasmic polyhedrosis virus (CPV) and hepatitis B virus (HBV), two long-term studied topics of our team, are chose here to demonstrate how using structural biology techniques to explore the viral genome, such as genome package and distribution, and mRNA transcribing/capping/releasing of viruses.

Author Details

Jian He
State Key Laboratory of Biocontrol, Guangzhou East Campus Lab Center, Sun Yat-sen University, China, China
Shuyu Liu
State Key Laboratory of Biocontrol, Guangzhou East Campus Lab Center, Sun Yat-sen University, China, China
Xiaoqin Zhong
State Key Laboratory of Biocontrol, Guangzhou East Campus Lab Center, Sun Yat-sen University, China, China
Jingchen Sun
Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding , College of Animal Science, South China Agricultural University, China, China
Zheng Liu
Markey Center for Structural Biology, Department of Biological Sciences, Purdue University, USA, USA
Jingqiang Zhang
State Key Laboratory of Biocontrol, Life Sciences School, Sun Yat-sen University, China, China

Citation

Jian He, Shuyu Liu, Xiaoqin Zhong, Jingchen Sun, Zheng Liu and Jingqiang Zhang. Structural Insights into the Genome of Viruses. In Genomics II: Bacteria, Viruses and Metabolic Pathways. ISBN:978-1-480254-145. iConcept Press. 0000.

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