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iConcept Journal of Emerging Issues in Medical Diagnosis and Treatment
Title
iConcept Journal of Emerging Issues in Medical Diagnosis and Treatment
Editor
Eugenia Giannopoulou
ISSN
2309-3528
Publisher
iConcept Press

iConcept Journal of Emerging Issues in Medical Diagnosis and Treatment

Vaccine trials in Africa: Impact and challenges

by Olubukola Idoko, Muhammed Afolabi, Bernhards Ogutu and Martin Ota

Volume: 5 (2016); Issue: 1
Status: Copy Editing and Typesetting

Abstract

Immunization remains the most cost effective method for the control and prevention of infectious diseases. As a consequence, an intensive global effort to deploy new vaccines for disease control and eradication is ongoing. These new vaccines should however be tested in the settings in which they will be deployed. This has led to the conduct of many vaccine trials in Africa and other parts of the developing world where several infectious diseases with significant public health impact are prevalent. However, some these areas have peculiarities and are just beginning to gain expertise in the conduct of such trials. Vaccine developers and sponsors of these trials are not always very conversant with some issues which are unique to the trial sites. This discrepancy in knowledge from both partners can result in considerable challenges. This chapter highlights the impact and challenges of conducting early and late phase vaccine trials in resource constrained settings and propose some ways of working through them.

Author Details

Olubukola Idoko
Vaccinology/Paediatrics, Medical Research Council Unit, The Gambia
Muhammed Afolabi
Disease Control and Elimination, Medical Research Council Unit, The Gambia
Bernhards Ogutu
Kenya Medical Research Institute, Kenya Medical Research Institute
Martin Ota
Immunization Division, WHO Regional Office for Africa

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