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iConcept Journal of Emerging Issues in Medical Diagnosis and Treatment
iConcept Journal of Emerging Issues in Medical Diagnosis and Treatment
Eugenia Giannopoulou
iConcept Press

iConcept Journal of Emerging Issues in Medical Diagnosis and Treatment

Parasitic diseases: Toxocara species infection associated with cardiovascular disease

by Mohammad Zibaei

Volume: 6 (2017); Issue: 1
Status: Copy Editing and Typesetting


Toxocariasis is the clinical term that applied to infection in the human host with Toxocara species larvae. Toxocara infection is a worldwide helminthic zoonosis that caused by the ascariid nematode, Toxocara species. Dogs and cats are the definitive hosts and act as reservoirs for Toxocara canis and Toxocara cati, respectively. Humans are infected by ingestion of embryonated eggs in the soil, and eating the meat of paratenic hosts containing encapsulated larvae. The larva hatches in the intestine and migrate into different organs, mainly the liver and lungs. It may occasionally migrate into the myocardium, kidney and central nervous system. There are clinical forms of toxocariasis such as visceral larva migrans, ocular larva migrans, covert toxocariasis, and neurotoxocariasis. Cardiovascular disease is the primary cause of death all around the world and accounted for up to 30 percent of all-cause mortality. Cardiovascular disease and more precisely atherosclerotic cardiovascular disease, is predicted to remain the single leading cause of death (up to 24 million deaths by 2030). A-quarter of people presenting the disease does not show any of the known cardiovascular risk factors. Therefore, there is considerable interest in looking for novel components affecting cardiovascular health, especially for those that could improve global cardiovascular risk prediction. The aim of this review is to investigate the clinical aspects, new diagnostic and therapeutic perspectives of toxocaral disease with cardiovascular manifestations.

Author Details

Mohammad Zibaei
Department of Parasitology and Mycology, School of Medicine, Alborz University of Medical Sciences, Iran

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